GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs7267979 | 1 | rs6050562 | chr20:25336186 | FAM182A | chr20:26035250-26067552:+ | 0.19 | 3.48 | 0.000553 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050562 | chr20:25336186 | FAM182B | chr20:25744102-25848786:- | -0.26 | -5.44 | 8.66E-8 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050562 | chr20:25336186 | NINL | chr20:25433338-25566153:- | 0.34 | 7.04 | 6.69E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050562 | chr20:25336186 | PYGB | chr20:25228706-25278647:+ | 0.14 | 3.59 | 0.000359 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050564 | chr20:25344231 | ENTPD6 | chr20:25176339-25207360:+ | 0.32 | 7.24 | 1.84E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050564 | chr20:25344231 | FAM182A | chr20:26035250-26067552:+ | 0.19 | 3.48 | 0.000539 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050564 | chr20:25344231 | FAM182B | chr20:25744102-25848786:- | -0.26 | -5.4 | 1.08E-7 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050564 | chr20:25344231 | NINL | chr20:25433338-25566153:- | 0.33 | 6.89 | 1.74E-11 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050564 | chr20:25344231 | PYGB | chr20:25228706-25278647:+ | 0.16 | 4.03 | 6.46E-5 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050565 | chr20:25347563 | ENTPD6 | chr20:25176339-25207360:+ | 0.32 | 7.31 | 1.17E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050565 | chr20:25347563 | FAM182A | chr20:26035250-26067552:+ | 0.18 | 3.41 | 0.000703 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050565 | chr20:25347563 | FAM182B | chr20:25744102-25848786:- | -0.25 | -5.15 | 3.85E-7 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050565 | chr20:25347563 | NINL | chr20:25433338-25566153:- | 0.33 | 6.73 | 4.92E-11 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050565 | chr20:25347563 | PYGB | chr20:25228706-25278647:+ | 0.16 | 3.96 | 8.64E-5 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050566 | chr20:25351071 | ENTPD6 | chr20:25176339-25207360:+ | 0.3 | 6.69 | 6.1E-11 | Liver enzyme levels (alkaline phosphatase) |